Dapoxetine
What is Dapoxetine?
Dapoxetine is a medication used for treating premature ejaculation in men. Johnson and Johnson is the manufacturer of this drug and it markets it in countries worldwide. It is available in tablet form.
How does it work?
Dapoxetine works to regulate premature ejaculation in men. Its working is based on inhibition of neuronal reuptake of serotonin and consequent potency of serotonin activity. Men taking Dapoxetine hydrochloride for their treatment of premature ejaculation experience significant improvements in their sexual activities like ejaculation control, satisfaction while sexual intercourse, and increment in intra-vaginal ejaculatory latency time.
What is the dosage of Dapoxetine?
According to the manufacturer of Dapoxetine, a dosage of 30mg or 60mg tablet should be taken 1-3 hours before sexual activity. However, the doctor’s recommendation should be followed for desirable results. The dosage should not be taken more than once in a day.
What results were seen in clinical trials?
In the phase two clinical trial of Dapoxetine, the efficacy and safety of 60mg and 100mg dosages were tested against placebo for the treatment of premature ejaculation among men. The results of the trial showed that use of Dapoxetine increased the intravaginal ejaculatory latency time (IELT) for both the 60mg and 100mg doses when compared to placebo. After 12 weeks of study, the trial researchers found that ejaculation time was 1.75 minutes among the placebo, 2.78 minutes for subject taking 30mg of Dapoxetine and 3.32 minutes for subjects taking 60mg of Dapoxetine.
What are the side effects of Dapoxetine?
Dapoxetine belongs to a class of drugs known as SSRI (Selective Serotonin Reuptake Inhibitors) and its use can result in some side effects on the user Common side effects of Dapoxetine are nausea, headache, diarrhoea, and dizziness. Use of Dapoxetine may also result in dermatological reactions. Some users of Dapoxetine may report upset stomach.
What are the contraindications for Dapoxetine?
· Dapoxetine is for men only. Women can not use this drug
· Patients who suffer from any other health problems should consult the doctor before taking Dapoxetine
· Patients taking antidepressants should inform the doctor before taking Dapoxetine
What are the precautions for Dapoxetine?
· Dapoxetine is not an aphrodisiac but a prescription drug. Therefore, men should not take it as sex drive enhancer
· Use of Dapoxetine may result in some psychiatric problems if taken without the recommendation of the doctor
· It may also result in weight gain. Patients should take dosages of this drug as directed by the doctor
· If patients report any undesirable side effects such as low sex drive or weakness, they should seek medical help
· Patients should take only the recommended dosage of Dapoxetine. Taking high dosage may result in serious side effects
Brief description
Dapoxetine is a used specifically for the treatment of premature ejaculation. Johnson and Johnson is the manufacturer of this drug. The mechanism of the drug action is thought to be linked to inhibition of neuronal reuptake of serotonin and consequent potency of serotonin activity. Some of the side effects of this drug are neuropsychiatry disorders, skin reactions, obesity, loss of libido, nausea, vomiting, headache, gastric upset and generalized weakness.